The demand for cannabidiol CBD products has been increasing and it is used for treating chronic pain, inflammations, anxiety, depression and many more ailments. This is due to its therapeutic and medical benefits which it imparts by enhancing the endocannabinoid system of our body. However, these positive healing effects of CBD products are dependent on multiple factors that also influence its dosing. This article will try to shed some light on those important factors influencing the effect of CBD products on our body; so, what are those factors?
The Type Of Extract Used
There are mainly three types of hemp extracts used to make CBD products, namely: full-spectrum hemp extract, broad-spectrum hemp extract and CBD isolate. Full-spectrum hemp extract contains all the natural cannabinoids found in the hemp plant, broad spectrum hemp extract is similar to full-spectrum hemp extract but with THC removed and CBD isolate is 99% pure CBD having the highest concentration.
Concentration is the amount of hemp CBD that is contained in a product or a serving of it and can also be called potency. This depends on the type of extract used to make the product and usually denoted in milligram (mg) of CBD. Also, the strain of the hemp plant from which the full-spectrum or broad-spectrum extract is made can also influence the concentration of CBD contained. So, when the amount of CBD contained increases the potency of the product increases.
The Quality Of Hemp Extract
The effect of a CBD product also depends on the quality of the hemp extract used and a high quality extract can give the maximum effect. It is determined by the cultivation methods like the type of soil and water used to grow the hemp plant. Some of the highest quality products use extracts from plants that use organic cultivation practises to ensure good quality hemp CBD. Besides, the quality of the hemp extract is determined by the extraction method used and high quality products usually employ CO2extraction methods. This is because the final product is highly pure without any toxic impurities in it.
Mode Of Administration
The effect of a CBD product depends on the mode of administration and different methods have varying times for the complete onset of effects. For example, inhaling cannabidiol vapours has the fastest onset time because it is directly absorbed into the bloodstream through the lungs. While, consuming it orally in the form of edibles or capsules has the slowest onset time as it has to pass through the digestive system. Oral consumption in the form of tinctures or lozenges has an onset time between these two. Here, you consume it sublingually by holding it under your tongue for up to 30 to 60 seconds or sucking it and absorbed into the bloodstream through the oral mucosa.
The Bioavailability Of The Product
The bioavailability is the amount of cannabidiol CBD that enters into the bloodstream and it depends on the method of administration. For example, on inhalation it passes directly into the bloodstream through lungs and the amount of CBD lost through filtration is minimal. Now, if you consume in the form of capsules or pills, it has to pass through the digestive tract and go through first pass metabolism there and the liver. Also the digestive enzymes and stomach acids destroy a significant portion of the cannabidiol consumed. This results in 80% of the CBD being excreted reducing the effectiveness of CBD products.
The Chemical Property Of CBD
CBD is hydrophobic, while it easily mixes in fats or lipids increasing its absorption into the body. So, mixing it with carriers such as medium-chain triglyceride (MCT) oil increases the absorption of oral products like pure CBD oil capsules. Some manufacturers use manufacturing techniques called nano emulsion where they breakdown the oil into tinier particle sizes, so that it easily dissolves and evenly distributed in solvents like water. As a result it is more easily absorbed into the bloodstream through the digestive system.
The Entourage Effect
The entourage effect of full-spectrum and broad-spectrum hemp CBD products can increase its bioavailability and give longer lasting effects. This is because the enzymes that metabolise CBD and the other phytocannabinoids are the same, making it available longer in the bloodstream.
The weight of the individual consuming the CBD product can significantly influence the quality of cannabidiol’s effect on the body. A heavier person will require a higher dose compared to a lighter person to feel the same degree effect. The other physiological factor is the individual metabolic rate; it varies from person to person as it depends on gender, health condition as well as the weight of the individual. If you are consuming any medicine for ailments there are chances that it can interact with CBD and decrease its effectiveness. However, you should also know that cannabidiol reduces the liver capacity to metabolise which can reduce its effectiveness.
The effect of the CBD product on your body also depends on its dosage. But, it is determined by the various factors discussed above like the concentration, weight, bioavailability and the type of extract used.
If you are planning to use cannabidiol CBD for an ailment or as a daily health supplement, it is advisable to consult with the physician before starting.